Research summary
Melanotan-2 has been studied in published cell, animal and small human studies of melanocortin receptor pharmacology. It is not an approved medicine, and regulators in several regions have issued warnings about unlicensed products. This summary describes what the literature has investigated. It is not a claim about the effects of our product, which is supplied for laboratory research only.
Mechanism of action
Melanotan-2 is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone. It is a non-selective agonist of melanocortin receptors, including MC1R, MC3R, MC4R and MC5R, which are involved in pigmentation, energy homeostasis and sexual function signalling.
Chemical properties
Structure: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 (cyclic lactam heptapeptide). Molecular formula: C50H69N15O9. Molecular weight: approx. 1024.2 g/mol. Form: lyophilised powder. Purity and identity: see the batch Certificate of Analysis (HPLC and mass spectrometry).
Storage and handling
Supplied as a lyophilised (freeze-dried) powder. Store sealed, cold, dry and protected from light, as stated on the Certificate of Analysis and product label. Allow the vial to reach room temperature before opening to limit condensation. Avoid repeated temperature cycling and humidity exposure. For laboratory research use only.
Literature references
Selected PubMed record on melanotan II, scientific background only, not claims about our product. PMID 31953620: melanotan II as a possible cause of renal infarction, review of the literature and case report (safety-related). Open any record at https://pubmed.ncbi.nlm.nih.gov/PMID/ . More: https://pubmed.ncbi.nlm.nih.gov/?term=melanotan+II
For laboratory research use only. Not for human or veterinary use. Nothing on this page is medical advice.
