{"title":"Weight Loss \u0026 Metabolic","description":"","products":[{"product_id":"tesamorelin-5mg","title":"Tesamorelin · 5mg","description":"\u003cp\u003e\u003cstrong\u003eTesamorelin\u003c\/strong\u003e is a synthetic analogue of growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification at the N-terminus for enhanced metabolic stability. It stimulates the anterior pituitary to secrete growth hormone in a physiological, pulsatile pattern, leading to downstream IGF-1 elevation and preferential visceral adipose tissue reduction. Research applications include GH axis modulation, visceral fat reduction models, metabolic syndrome research, and HIV-associated lipodystrophy biology.\u003c\/p\u003e\u003cp\u003eSynthesised and lyophilised in Zürich to \u0026gt;99% HPLC purity. Lot-traceable with full COA available upon request.\u003c\/p\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eTechnical Specifications\u003c\/strong\u003e\u003c\/summary\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eTesamorelin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e218949-48-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC221H366N72O67S\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e5135.77 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStructure\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e44-amino acid GHRH analogue with trans-3-hexenoic acid N-terminus modification\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;99% (HPLC-UV)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised Powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-20C, protect from light and moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water or sterile saline\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eResearch \u0026amp; Literature\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eTesamorelin (Egrifta) received FDA approval for HIV-associated lipodystrophy. Key studies by Falutz et al. demonstrated significant visceral adipose tissue reduction in clinical trials. Research has also explored its role in metabolic syndrome, cognitive function in older adults, and growth hormone axis modulation. The trans-3-hexenoic acid modification at the N-terminus significantly extends its biological half-life compared to endogenous GHRH.\u003c\/p\u003e\u003c\/details\u003e\u003cp\u003e\u003cem\u003eFor research purposes only. Not for human consumption. Supplied in accordance with EU Regulation (EC) No 1907\/2006 (REACH) for research and analytical use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Zürich BioGenix","offers":[{"title":"Default","offer_id":53670369558865,"sku":"ZBG-TESA-5","price":89.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1039\/8718\/3953\/files\/IMG-4571.png?v=1779826215"},{"product_id":"tesamorelin-10mg","title":"Tesamorelin · 10mg","description":"\u003cp\u003e\u003cstrong\u003eTesamorelin\u003c\/strong\u003e is a synthetic analogue of growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification at the N-terminus for enhanced metabolic stability. It stimulates the anterior pituitary to secrete growth hormone in a physiological, pulsatile pattern, leading to downstream IGF-1 elevation and preferential visceral adipose tissue reduction. Research applications include GH axis modulation, visceral fat reduction models, metabolic syndrome research, and HIV-associated lipodystrophy biology. This 10mg format provides an extended research supply.\u003c\/p\u003e\u003cp\u003eSynthesised and lyophilised in Zürich to \u0026gt;99% HPLC purity. Lot-traceable with full COA available upon request.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research purposes only. Not for human consumption. 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MOTS-C has been studied in the context of exercise mimetics, longevity signalling, age-related metabolic decline, and mitochondrial biology.\u003c\/p\u003e\u003cp\u003eSynthesised and lyophilised in Zürich to \u0026gt;99% HPLC purity. Lot-traceable with full COA available upon request.\u003c\/p\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eTechnical Specifications\u003c\/strong\u003e\u003c\/summary\u003e\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eChemical Name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMOTS-C (Mitochondrial ORF of 12S rRNA type-C)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1627580-64-6\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC101H152N28O22S2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2174.53 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMet-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16 AA)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u0026gt;99% (HPLC-UV)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised Powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e-20C, protect from light and moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic water or sterile saline\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eResearch \u0026amp; Literature\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eMOTS-C was first characterised by Lee et al. (2015) in Cell Metabolism as a novel mitochondria-derived peptide encoded by the 12S rRNA region of the mitochondrial genome. Research has demonstrated its role in regulating insulin sensitivity, skeletal muscle glucose uptake, and adipogenesis through AMPK activation and FOXO pathway modulation. Studies in aged mice showed that systemic MOTS-C administration restored youthful metabolic homeostasis and improved exercise capacity, suggesting a role in longevity signalling.\u003c\/p\u003e\u003c\/details\u003e\u003cp\u003e\u003cem\u003eFor research purposes only. Not for human consumption. Supplied in accordance with EU Regulation (EC) No 1907\/2006 (REACH) for research and analytical use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Zürich BioGenix","offers":[{"title":"Default","offer_id":53670369624401,"sku":"ZBG-MOTS-10","price":99.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1039\/8718\/3953\/files\/IMG-4568.png?v=1779825949"},{"product_id":"mots-c-40mg","title":"MOTS-C · 40mg (6-Week Supply)","description":"\u003cp\u003e\u003cstrong\u003eMOTS-C\u003c\/strong\u003e is a 16-amino acid mitochondrial-derived peptide (MDP) encoded within the 12S rRNA region of the mitochondrial genome. It acts as a metabolic regulator that translocates to the nucleus under metabolic stress, where it activates AMPK and the FOXO pathway to improve insulin sensitivity, fatty acid oxidation, and skeletal muscle glucose uptake. MOTS-C has been studied in the context of exercise mimetics, longevity signalling, age-related metabolic decline, and mitochondrial biology. This 40mg format provides an extended research supply.\u003c\/p\u003e\u003cp\u003eSynthesised and lyophilised in Zürich to \u0026gt;99% HPLC purity. Lot-traceable with full COA available upon request.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eFor research purposes only. Not for human consumption. Supplied in accordance with EU Regulation (EC) No 1907\/2006 (REACH) for research and analytical use.\u003c\/em\u003e\u003c\/p\u003e","brand":"Zürich BioGenix","offers":[{"title":"Default","offer_id":53670369657169,"sku":"ZBG-MOTS-40","price":219.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1039\/8718\/3953\/files\/IMG-4569.png?v=1779826043"}],"url":"https:\/\/zurichbiogenix.com\/collections\/weight-loss-metabolic.oembed","provider":"Zürich BioGenix","version":"1.0","type":"link"}